Diagnosing Periprosthetic Infection: False-positive Intraoperative Gram Stains

Leuconostoc mesenteroides periprosthetic knee infection, an unusual fastidious Gram-positive bacteria: a case report

BACKGROUND Periprosthetic joint infections are mainly caused by Gram-positive cocci. Leuconostoc mesenteroides is a rare microorganism mainly causing bloodstream infections. At times, it might be confused with another type of cocci and give rise to misdiagnosed infections. Molecular diagnosis and biofilm production comprise important techniques to guide antibiotic treatment. CASE PRESENTATION...

Prevention of periprosthetic joint infection: pre- and intraoperative considerations.

Total joint arthroplasty (TJA) is the ultimate treatment for degenerative joint disease. For the majority of patients, it leads to regained function and improved quality of life. By 2030, the total number of primary total knee arthroplasty (TKA) procedures performed annually in the United States is expected to reach nearly 3.48 million, a 673% increase from the number performed in 2005. Further...

Prevention of Periprosthetic Joint Infection

Prosthetic joint infection (PJI) is a calamitous complication with high morbidity and substantial cost. The reported incidence is low but it is probably underestimated due to the difficulty in diagnosis. PJI has challenged the orthopaedic community for several years and despite all the advances in this field, it is still a real concern with immense impact on patients, and the healthcare system....

False positive auto-antibodies in HIV infection.

Unyvero i60 implant and tissue infection (ITI) multiplex PCR system in diagnosing periprosthetic joint infection.

Periprosthetic joint infection (PJI) is one of the most challenging complications in orthopedic surgery. In cases of suspected periprosthetic joint infection several diagnostic methods are available. In this study we investigated the performance of the newly available Unyvero i60 implant and tissue infection (ITI) multiplex PCR System. 62 specimens from 31 patients with suspected PJI or aseptic...